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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPG2
All Species:
7.27
Human Site:
S2623
Identified Species:
16
UniProt:
P98160
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98160
NP_005520.4
4391
468798
S2623
T
I
Q
G
S
G
S
S
H
V
P
S
V
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099299
4392
468662
S2624
T
I
Q
G
S
G
S
S
H
V
P
S
V
S
P
Dog
Lupus familis
XP_535371
2720
290354
G1054
C
L
K
C
F
C
M
G
V
S
R
Q
C
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q05793
3707
398275
S2041
I
M
I
S
V
S
P
S
T
N
S
P
P
A
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518520
1150
124768
Chicken
Gallus gallus
NP_001001876
4071
432826
C2405
A
D
S
G
E
Y
V
C
R
V
T
T
G
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001120939
3407
371297
N1741
N
G
I
L
T
I
Q
N
V
Q
P
E
D
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027037
4179
461773
L2467
V
Q
G
G
N
L
Y
L
Y
D
L
Q
V
S
D
Honey Bee
Apis mellifera
XP_393220
3382
373579
R1716
L
D
I
P
T
A
P
R
T
I
V
I
P
P
S
Nematode Worm
Caenorhab. elegans
Q06561
3375
369033
I1709
I
T
P
Q
T
Q
T
I
P
E
G
D
P
A
R
Sea Urchin
Strong. purpuratus
XP_001186142
2326
251883
Y659
Q
V
R
I
T
G
N
Y
T
S
A
Q
W
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.8
51.7
N.A.
72.7
N.A.
N.A.
20.8
58.1
N.A.
45.2
N.A.
22.1
25.7
24.2
24.2
Protein Similarity:
100
N.A.
98.6
54.6
N.A.
77.8
N.A.
N.A.
23.2
69.8
N.A.
57.4
N.A.
35.9
39.4
37.9
34.7
P-Site Identity:
100
N.A.
100
0
N.A.
13.3
N.A.
N.A.
0
20
N.A.
6.6
N.A.
20
0
0
6.6
P-Site Similarity:
100
N.A.
100
20
N.A.
26.6
N.A.
N.A.
0
26.6
N.A.
26.6
N.A.
33.3
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
10
0
0
28
0
% A
% Cys:
10
0
0
10
0
10
0
10
0
0
0
0
10
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
10
0
10
10
0
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
37
0
28
0
10
0
0
10
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% H
% Ile:
19
19
28
10
0
10
0
10
0
10
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
10
0
10
0
10
0
0
10
0
0
0
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
10
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
19
0
10
0
28
10
28
10
28
% P
% Gln:
10
10
19
10
0
10
10
0
0
10
0
28
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
10
10
0
10
0
0
10
19
% R
% Ser:
0
0
10
10
19
10
19
28
0
19
10
19
0
37
19
% S
% Thr:
19
10
0
0
37
0
10
0
28
0
10
10
0
10
0
% T
% Val:
10
10
0
0
10
0
10
0
19
28
10
0
28
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
10
10
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _